Intended Use
For the in vitro quantification of human phosphorylated tau-181 protein in human serum. Alzheimer's disease (AD), also known as senile dementia, is a common degenerative disease of the central nervous system, caused mainly by neuronal tangles (NFT) due to hyperphosphorylation of tau protein in the brain and by the deposition of large amounts of β-amyloid in the brain, resulting in abnormal neuronal function. As the disease worsens, the pathological changes in NFT are dominated by hyperphosphorylation of tau protein, and therefore the serum concentration of human phosphorylated tau-181 protein (P-tau-181) is significantly increased in patients with mid- to late-stage AD. Commonly used clinical and laboratory methods to detect P-tau-181 include chemiluminescence, immunochromatography and enzyme-linked immunoassay

Specifications

Main Components

1. P-tau-181 test strip in a sealed pouch with desiccant...............25 tests
2. Sample diluent..........................................................................25 pieces
3. QR code card for calibration.......................................................1 piece
4. User manual...............................................................................1 piece
5. Quantitative suction and dropping tube (Optional).

Storage And Validity

1. Store the test kit at 4℃~30℃ up to the expiration date printed on package.
2. Test strip should be used within 1 hour once the foil pouch is opened.

Applicable Device

1. LS-1100 Dry Fluorescence Immunoassay Analyzer
2. LS-2100 Dry Fluorescence Immunoassay Analyzer
3. LS-4000 Dry Fluorescence Immunoassay Analyzer
4. LS-3000 Automatic Fluorescence Immunoassay Analyzer